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Year : 2017  |  Volume : 31  |  Issue : 1  |  Page : 28-34

Dexmedetomidine in supraclavicular block: Effects on quality of block and analgesia

1 Department of Anesthesia, Choithram Hospital and Research Center, Indore, Madhya Pradesh, India
2 Department of Anesthesia, PramukhSwami Medical College, Karamsad, Gujarat, India

Correspondence Address:
Avani P Shah
5/A, Everest Park Society, Opp. Matangi Flate, Gordhanwadi Tekra, Kankaria, Ahmedabad - 380 028, Gujarat
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijpn.ijpn_10_17

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Context and Objectives: Upper limb surgeries are most commonly performed under brachial plexus block (BPB). A variety of adjuvants have been used to enhance the effect of local anesthetics in peripheral nerve block. We evaluated the effect of dexmedetomidine as an adjuvant to 0.25% bupivacaine in supraclavicular block (SCB) in terms of onset and duration of sensory and motor block, analgesia, and quality of block. Subjects and Methods: Sixty American Society of Anesthesiologists physical status I and II patients undergoing upper limb surgery, in which SCB was used, were enrolled. Patients were assigned to one of the following groups alternatively: Group C received BPB with bupivacaine 0.25% (34 ml) + normal saline 1 ml. Group D received BPB with bupivacaine 0.25% (34 ml) + dexmedetomidine 1 μg/kg. Onset and duration of sensory and motor block, duration of analgesia, sedation score, and hemodynamic parameters were studied in both the groups. Results: There were no significant differences in patient and surgery characteristics between two groups. In Group D, shorter time to onset of sensory block (09.8 vs. 15.3 min, P = 0.006) and longer duration (691.3 vs. 395.6 min, P = 0.006) was observed. Onset time to achieve motor block (11.8 vs. 17.3 min, P = 0.009) was also short and duration was longer (637 vs. 367.6 min, P< 0.001) in Group D. Duration of analgesia (735.6 vs. 423.6 min, P< 0.001) was higher as compared to control group. Conclusions: Adding dexmedetomidine to bupivacaine during supraclavicular BPB shortens sensory and motor block onset time, increases the sensory and motor block duration, and prolongs the duration of postoperative analgesia without any significant side effect.

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